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Despite the nonsignificant effects found from all these tests, the trend of the improvement was reported for the 2-minute step test, time up and go test, shoulder strength test, and PEFR test

Diabetes & vascular disease research

Robertson et al., 2016), left lenticular nucleus(Harada et al., 2011), occipital cortex(Drenthen et al., 2016

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118 Furthermore, cerebral hyperinsulinemia is associated with diminished clearance of A peptides due to the competitive inhibition of insulin-degrading enzyme, a metalloprotease responsible for degrading both insulin and A, which preferentially binds insulin over A under hyperinsulinemic conditions

doi: 10.1124/pharmrev.121.000408 16